Enhanced colon cancer chemoprevention of curcumin by nanoencapsulation with whey protein
نویسندگان
چکیده
منابع مشابه
Curcumin for chemoprevention of colon cancer.
The most practical approach to reduce the morbidity and mortality of cancer is to delay the process of carcinogenesis through the use of chemopreventive agents. This necessitates that safer compounds, especially those derived from natural sources must be critically examined for chemoprevention. A spice common to India and the surrounding regions, is turmeric, derived from the rhizome of Curcuma...
متن کاملNanoencapsulation of pomegranate bioactive compounds for breast cancer chemoprevention
Pomegranate polyphenols are potent antioxidants and chemopreventive agents but have low bioavailability and a short half-life. For example, punicalagin (PU), the major polyphenol in pomegranates, is not absorbed in its intact form but is hydrolyzed to ellagic acid (EA) moieties and rapidly metabolized into short-lived metabolites of EA. We hypothesized that encapsulation of pomegranate polyphen...
متن کاملSphingolipids in the chemoprevention of colon cancer.
Sphingolipids were first described more than 100 years ago by the physician Thudicum who named the fatty substance he found in brain, sphingosin. Among multiple other functions, sphingolipids are lipid messengers in the signaling pathways of growth factors, cytokines, cellular stresses and others. As such, they are involved in the regulation of a wide spectrum of processes that modulate cell gr...
متن کاملChemoprevention of colon carcinogenesis by dietary curcumin, a naturally occurring plant phenolic compound.
Human epidemiological and laboratory animal model studies have suggested that nonsteroidal antiinflammatory drugs reduce the risk of development of colon cancer and that the inhibition of colon carcinogenesis is mediated through the alteration in cyclooxygenase metabolism of arachidonic acid. Curcumin, which is a naturally occurring compound, is present in turmeric, possesses both antiinflammat...
متن کاملCurcumin, a Naturally Occurring Plant Phenolic Compound Chemoprevention of Colon Carcinogenesis by Dietary
Human epidemiological and laboratory animal model studies have suggested that nonsteroidal antlinflammatory drugs reduce the risk of development of colon cancer and that the inhibition of colon carcinogen esis is mediated through the alteration in cyclooxygenase metabolism of arachidonic acid. Curcumin, whichis a naturally occurring compound,is present in turmeric, possesses both antiinflammato...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: European Journal of Pharmacology
سال: 2016
ISSN: 0014-2999
DOI: 10.1016/j.ejphar.2016.07.017